Hong J observed detection rate of H. pylori Urase-IgG and H. pylori CagA-IgG in peripheral blood of 39 rosacea patients [20], the results showed that the total incidences of H. pylori Urase-IgG and H. pylori CagA-IgG in all 39 rosacea patients were not high, but the incidence rates in rosacea patients with digestive tract symptoms were 86. Here, S100A8 is linked to rosacea.