KDR and diabetes mellitus: We previously demonstrated that Lin-/VEGF-R2+ EPCs defined as Lin−/VEGF-R2+ were more primitive than other Lin-/VEGF-R2+ EPCs described in literature and due to diabetes they had limited vascular repair capacity attributed to their impaired ability to mobilize, rather than their ability to proliferate, leading to Lin-/VEGF-R2+ EPCs BM trapping [2, 7, 31].