SNCA and early-onset autosomal dominant Alzheimer disease: Along the same lines, there may exist a disease spectrum of synucleins, such as in multiple system atrophy, Dementia with Lewy bodies (DLBs), Alzheimer's disease, nerve degeneration with iron ion deposition (type N BIA 1), simple autonomic nervous breakdown, type I spinal cerebellar ataxia, subtype specific tremor, and so on,[31] among whom positive results may have occurred.