Hypoalbuminaemia can be seen as an independent risk factor for morbidity and mortality of illness.[28] Albumin levels also are indicative of inflammatory status.[29,30] Low albumin concentrations reflect low serum protein levels, leading to low bactericidal activity of serum and predisposing to bacterial infections.[31] Hypoalbuminaemia may be related to inflammatory changes in the sepsis process or be a reflection of poor baseline nutrition levels. This evidence concerns the gene ALB and bacterial infectious disease.