CRP and infection: The inflammatory response to infection and tissue injury supports host defense, clearance of necrotic tissue, adaptation, and repair, while the purpose of low-grade inflammation appears to be restoration of metabolic homeostasis.27 The increased CRP levels found in RSE patients in our study may be due to their young age, resulting in a more prominent inflammatory response, and the respiratory injury, particularly pulmonary parenchyma, often seen in RSE patients as compared to LSE patients.