ZFP36L1 can also act as a tumour suppressor to influence tumorigenesis through negatively regulating VEGFA and Bcl2 expression.40, 41 However, the role of ZFP36L1 in adipogenesis has only been implicated by the report that it could enhance the degradation of PPARγ2 mRNA transcript in 3T3‐L1 preadipocytes.42 In this study, through lentiviruses‐mediated ZFP36L1 over‐expression and knockdown assay, we demonstrated that ZFP36L1 functions in the downstream of levamisole and acts as a negative regulator in the adipogenic differentiation of the human AA BM‐MSCs. The gene discussed is PPARG; the disease is neoplasm.