HOXA11 and central nervous system cancer: By employing the siRNA transfection, downregulation of the HOXA11‐AS expression repressed the cell proliferation via inducing cell cycle arrest at the G0/G1 phase and promoted the apoptosis in glioma cell lines as well as xenograft mouse model.17, 18 MiR‐140‐5p was downregulated in glioma cells, and miR‐140‐5p was found to be directly targeted HOXA11‐AS at 3′‐UTR via the bioinformatics analysis and luciferase assay.