HOXA11 and central nervous system cancer: HOXA11‐AS was significantly overexpressed in surgically excised glioma tissue compared with adjacent nontumor tissue.17, 18 And elevated HOXA11‐AS indicates a short survival and a poor prognosis in glioma patients.17, 18 The significant difference in HOXA11‐AS expression among glioblastoma (GBM) subtypes revealed by the mRNA microarray may indicate that HOXA11‐AS may also serve as a marker for glioma molecular subtype.17 The expression level of HOXA11‐AS was also significantly elevated in glioma cell lines (U251 and SHG44) when compared with normal human astrocytes.