NFKB1 and neoplasm: Programmed cell death ligand 1 expression levels in tumor cells have been reported to be positively correlated with tumor stage, metastasis, and recurrence rate.9 The expression of PD‐L1 is regulated by a variety of factors, such as signal transducer and activator of transcription (STAT), nuclear factor kappa B (NF‐κB), and nuclear factor of activated T cells (NFAT).10, 11 Li et al12 reported that glycogen synthase kinase 3β (Gsk3β) promotes the phosphorylation‐dependent proteasome pathway degradation of PD‐L1.