WNT16 and melanoma: The Wnt family of secreted glycoproteins induces signaling involved in processes of cell proliferation, differentiation, and oncogenesis, including colon cancer and melanoma; more than 90% of CRCs involve β-catenin-dependent WNT signal transduction.31 F7+F3 treatment reduced most differentially expressed genes related to Wnt signaling pathways, including, by a factor of eight, Wnt16 (geneID: 51384) that was previously shown to be involved in leukemia.32