Several genes linked to asthma are regulated by epigenetic mechanism, such as genes involved in T-effector pathways (interferon INF-γ, interleukin-4 (IL-4), IL-13, and IL-17), T-regulatory pathways (forkheadbox P3 [FoxP3]), and airway inflammation (arginase [ARG]) [112]. The gene discussed is IL4; the disease is asthma.