An intestinal immune network for IgA production might provide new markers in enteric DLBCL, such as CCR10, TNFRSF13B, AICDA, and HLA-DOB, as well as genes involved in transcriptional misregulation in cancer (NFKBIZ, FUT8, LMO2, CCND2, BCL2A1, ETV6, and CDK14). This evidence concerns the gene HLA-DOB and diffuse large B-cell lymphoma.