Therefore, we derived Spearman's correlations between the serum concentrations of IL-8 and eotaxin-1 and the expression levels of 8,061 genes, the levels of which were altered (FDR<0.05) in CD4+ cells of four CRC patients compared to five healthy volunteers (Supplemental Table 2). This evidence concerns the gene CXCL8 and colorectal carcinoma.