HMGA2 and lipoma: However, molecular karyotyping detected an unbalanced rearrangement of the <i>LPP</i> locus, not involving the <i>HMGA2</i> locus, which is the most frequent translocation partner observed in benign mesenchymal tumors such as lipomas (of soft tissue as well as parosteal) and pulmonary chondroid hamartoma.