Often, diuretic treatment is used in conjunction with angiotensin-converting-enzyme inhibitors (ACE inhibitors), Ca2+ channel blockers, or beta-blockers to regulate cardiac output, rate, and contraction and α1-adrenergic receptor blockers to control the tone of peripheral resistances, to surgical treatment to remove hormone hypersecreting adenomas, and to better address the underlying mechanism(s) responsible for the sustained increased in blood pressure [3, 4]. Here, ACE is linked to adenoma.