ALB and clostridium difficile infection: One of the most widely used and convenient scoring systems from the European Society of Clinical Microbiology and Infectious Disease indicates severe versus nonsevere CDI if one of the following are present: white blood cell count is greater than or equal to 15,000 cells/mm3, serum albumin < 3 g/dl, and/or serum creatinine level is greater than or equal to 1.5 times the premorbid level [10].