It could also prove to be an adjunct in cases of hematologic malignancies wherein an alteration of ABH antigens has been noted.11 Moreover, many studies have correlated the secretor status and many systemic illnesses like ankylosing spondylitis, peptic ulcer, ovarian cysts, and even squamous cell carcinoma.12 Thus, dried salivary samples proved to be a reliable source for ABO blood grouping; however, for the detection of D antigen, a more technique-sensitive approach needs to be developed. This evidence concerns the gene ABO and squamous cell carcinoma.