KBTBD7 and myocardial infarction: The myocardial infarct sizes at day 7 and scar tissue percent circumferences at day 28 after MI were significantly increased in miR-21-deficient mice than those in wild-type mice, whereas KBTBD7 silencing in vivo reduced the myocardial infarct and scar sizes in miR-21-deficient mice (Fig. 7b–d; Fig. S12).