TP53 and cancer: Functional annotation revealed that mRNAs in the ceRNA network were mainly involved in seven GO terms (Fig. 4c), and KEGG pathways including Hematopoietic cell lineage, Gap junction, Focal adhesion, Complement and coagulation cascades and a well-established cancer pathway, p53 signaling pathway64 (Fig. 4d and Supplementary Table S2).