Hence, our data confirm that all seven nodes of the linking region between three cancer networks (RXRA, MAP3K7, NR3C1, PABPC1, NDRG1, RELA and CTNNB1) have a role in the cancerogenesis of BlC, KiC and PrC and suggest that they can be used as biomarker to improve the diagnosis and prognosis of these three cancers. Here, RELA is linked to cancer.