Hence, our data confirm that all seven nodes of the linking region between three cancer networks (RXRA, MAP3K7, NR3C1, PABPC1, NDRG1, RELA and CTNNB1) have a role in the cancerogenesis of BlC, KiC and PrC and suggest that they can be used as biomarker to improve the diagnosis and prognosis of these three cancers. This evidence concerns the gene PPRC1 and cancer.