For example, Yang et al15 found the sensitivity and specificity of 75% and 100%, respectively, at the cut‐off value of 300 pg/mL; Oh et al16 showed 85.7% sensitivity and 90.2% specificity at cut‐off value of 63 pg/mL; Nisman et al17 demonstrated a new assay of plasma proGRP distinguishing SCLC from NSCLC with 80.4% sensitivity and 96.3% specificity at cut‐off value of 140 pg/mL. This evidence concerns the gene GRP and small cell lung carcinoma.