The median level of NSE was 35.06 pg/mL (24.13‐73.43 pg/mL) in SCLC patients, 12.26 pg/mL (10.42‐15.57 pg/mL) in NSCLC patients and 11.14 pg/mL (9.44‐13.79 pg/mL) in benign lung diseases. This evidence concerns the gene ENO2 and non-small cell lung carcinoma.