TACSTD2 and gelatinous drop-like corneal dystrophy: In 1999, Tsujikawa et al. [78] identified an inherited mutation in the TROP-2 gene, TACSTD2, as the cause of GDLD, which was first recognized as an autosomal recessive disease leading to the development of severe corneal amyloidosis and blindness in Japanese in 1914 by Nakaizumi [79], but later also identified in other nationalities [80], including other mutations of TACSTD2 [80].