The association of IL-10 with autoimmune disease is well established (Llorente et al., 1994), while its relationship with type 1 DM (Kikodze et al., 2013) and type 2 DM (Thorand et al., 2005; Brauner et al., 2014) has only been preliminarily defined, and its exact role in GDM has not yet been well established. The gene discussed is IL10; the disease is gestational diabetes.