MT4, characterized by the overall low level of fecal metabolites, had a high abundance of Fusobacterium and Desulfovibrionaceae, which are known to be overrepresented in patients with colon cancer and ulcerative colitis and to be involved in inflammation (Ohkusa et al., 2003; Rowan et al., 2010; Castellarin et al., 2012; Figliuolo et al., 2017). The gene discussed is MT4; the disease is ulcerative colitis.