CD8A and systemic lupus erythematosus: These cells were termed “Ts cells.” Similarly, autoantigen-specific CD8+ Tregs including CD8+CD28− cells have been induced in vitro via stimulation of peripheral T cells obtained from patients with systemic lupus erythematosus and has a supplemental common gamma chain (γc) cytokine cocktail including IL-2, IL-7, and IL-15 (21).