In spite of the negative correlations between the tumour weight and the percentages of CD3+ T, CD4+ T and CD19+ B lymphocytes and NK cells in spleen that were found only in H4R-KO mice at day 28 p.i. (Supplementary Table 3), no differences were found in the percentages of CD4+ T or CD8+ T, CD19+ B, NK cells in spleens of tumour bearing H4R-KO mice compared to WT mice (Table 1). This evidence concerns the gene CD4 and neoplasm.