To also address the role of STAT3 in HH/GLI‐driven BCC growth, we depleted by RNAi the expression of Stat3 in murine Ptch‐deficient BCC cells and compared the in vivo growth of Stat3‐deficient BCC cells with that of Stat3‐proficient controls. Here, PTCH1 is linked to skin basal cell carcinoma.