SLCO1A2 and supranuclear palsy, progressive, 1: We did observe that five of these genes were found to be highly expressed in the brain, with three of these genes being mainly expressed in the brain (SLCO1A2, C12 orf39 and SLCO1C1), and in regions affected in PSP (including the substantia nigra, caudate, putamen, and nucleus accumbens).