Consistent with these results, the Transwell assay with Matrigel suggested that PDBu or HGF could induce invasion of lung cancer cells (70.6 versus 156.6, P = 0.0001 for HGF, and 4.2 versus 76.2, P < 0.0001 for PDBu, Fig. 3f). Here, HGF is linked to lung carcinoma.