SMAD7 and colorectal carcinoma: The variant rs11874392 in SMAD7 (adjusted OR 1.16) was reported by Jiang and others [47] to be associated with CRC in a population-based study of non-Hispanic white subjects, but with odds ratio less than 1 (OR 0.80), whereas it was noted to be positively associated with CRC in Hispanics by Schmit and others (OR = 1.27) [48].