Furthermore, CBG derivatives showed anti-inflammatory properties, such as CBG quinone derivatives that reduced the release of TNF-α and IL-1β in the medium of LPS-treated BV2 cells [11] and the expression of TNF-α and IFN-γ in the spinal cord of a murine model of Experimental Autoimmune Encephalomyelitis (EAE) [10]. Here, IL1B is linked to experimental autoimmune encephalomyelitis.