Similarly to VER or CSA in R and T cells, LP117, a novel commercially available drug-specific modulator of P-gp-mediated drug transport (http://www.medkoo.com/products/14425) was also not able to depress JC-1 transport in P-gp-positive neuroblastoma cells, even if this substance in the same cells induced the effective efflux blockage of vincristine, vinorelbine, actinomycin D, paclitaxel, and Calcein/AM [27]. This evidence concerns the gene PGP and neuroblastoma.