Yet; in spite of the upregulated levels of this paracrine and angiogenic mediators and its receptors, they failed to displayed the very robust levels of receptor activation shown in Fig 1 for PDGFRA and PDGFRB, further reinforcing the idea of the predominance of PDGFR oncogenic signaling in KSHV-infected KS-like tumors. Here, PDGFRA is linked to Kaposi's sarcoma.