CCL2 and pseudotumor cerebri: Investigation of the cytokine and chemokine profiles in both the serum and CSF of patients with IIH has shown a significantly increased level of chemokine profiles in both the serum and CSF of patients with IIH has shown a significantly increased level of the chemokine CCL2 in the CSF of patients with IIH compared with controls, whereas CCL8, CCL7, and IL-1α were increased in the plasma in IIH, but not significantly (25).