PBML patients were significantly older; had lowered WBC counts, ANCs, hemoglobin levels, platelet (PLT) counts, and IgG levels; higher serum levels of LDH, ferritin, total bilirubin (T‐Bil), AST, alkaline phosphatase (ALP), and triglycerides; longer prothrombin times (PTs); and a higher incidence of splenomegaly and leukoerythroblastosis in PB smears. Here, F2 is linked to Splenomegaly.