Our previous work in a rodent model of diabetes demonstrated that increasing circulating GLP‐1 with a dipeptidyl peptidase‐4 (DPP4) inhibitor augments the impact of an aerobic exercise training regimen in a rat model of insulin‐resistant diabetes via augmentation of vascular mitochondrial respiration, content, and ATP production (Keller et al. This evidence concerns the gene GLP1R and diabetes mellitus.