TNFSF10 and neoplasm: Curcumin and BCG share pathways responsible for a tumor selective antiproliferative effect by suppressing transcription factors, like NF-κB, responsible for proliferation, invasion, and angiogenesis [7, 11–13], and by inducing apoptosis via TRAIL [7, 15]. In vitro and in vivo evidence indicate additive effects of curcumin and BCG treatment for UC [7]: Intratumorally administered BCG combined with oral fed curcumin immediately after tumor grafting resulted in a significant reduction in tumor volume compared to BCG alone, curcumin alone, or placebo.