Recently, Li et al. found that FBP1 downregulation could enhance the activity of Wnt/β-Catenin pathway and increase the level of its downstream targets, including c-Myc and MMP7 in human breast cancer cells [25–27], suggesting that FBP1 might take part in regulating cancer cell migration via Wnt/β-catenin signaling pathway. The gene discussed is FBP1; the disease is cancer.