Interleukin 6 (IL-6), which is involved in various physiological functions including neurodevelopment, haematopoiesis, bone metabolism, and immunity [1–4], is implicated in many inflammatory diseases, such as asthma, arthritis, osteoporosis, diabetes, cancer, ulcerative colitis, and Crohn's disease, and plays an important role in inflammation and immune diseases [5–7]. This evidence concerns the gene IL6 and Arthritis.