In J82 bladder cancer cells, the stimulation induced by rhGH (125.2 pg/ml) was diminished by 64.6±24.4% (p > 0.05) in the presence of MR-409 and by 43.8±12.0% (p > 0.05) following the exposure to GHRH(1-29)NH2. This evidence concerns the gene GHRH and urinary bladder cancer.