It has been established that the tumor periphery exhibits highly active VEGF‐associated angiogenesis, which increases the number and size of vessels by accelerating endothelial cell differentiation/proliferation, primitive vessel generation, vasodilation, and vessel lengthening.24, 25, 26, 27 In our histopathological examinations, these processes manifested as high VEGFR2 and CD31 expression in the tumor periphery. Here, KDR is linked to neoplasm.