Therefore, we evaluated the effects of the six FMR1 genotypes (i.e. low, normal and high repeat numbers for each allele) on the FMR1 mRNA expression profile in GCs, using GCs obtained from women with different ovarian response patterns: women with poor ovarian response (POR), women with normal ovarian function (NOR), and women with polycystic ovary syndrome (PCOS). The gene discussed is FMR1; the disease is polycystic ovary syndrome.