Meanwhile, the result of subgroup analysis on ethnicity showed significant associations between paraoxonase 1 activity and DM in Asian group (SMD = −2.00, 95% CI = −2.56 ∼ −1.44, P = .000, Supporting information Figure S1), but not in non‐Asian group (SMD = −0.44, 95% CI = −0.91 ∼ 0.03, P = .069, Supporting information Figure S1). This evidence concerns the gene PON1 and diabetes mellitus.