TMEM43 and arrhythmogenic right ventricular dysplasia 5: Previous studies have revealed TMEM43 pS358L mutation as a commonly genetic mutation in ARVD5 patients in several cohorts worldwide (Baskin et al., 2013; Christensen et al., 2011; Haywood et al., 2013; Merner et al., 2008; Milting et al., 2015).