CXCL1 and atherosclerosis: Compared with mice treated with control LNAs, treatment with lncWDR59-TSBs reduced atherosclerosis, the necrotic core area, and endothelial DNA damage, and increased EC proliferation (Fig. 7a–c), whereas the fibrous cap thickness and the Cxcl1-expressing ECs (Supplementary Figure 7H) were not affected (Fig. 7a).