When we stratified the L1CAM expression according to the stage of the tumor (<1B vs ≥ 1B) and the histotype (ADK) we found that high level of L1CAM were associated with lower DFS in patients with stage of tumor <1B and G3 grading (p = 0.006 and p = 0.01, respectively) (Fig. 4a and c); the expression of L1CAM did not predict risk of recurrence in patients with stage of the tumor ≥1B or in not EC (p = 0.14 and p = 0.25, respectively) (Fig. 4b and d). The gene discussed is L1CAM; the disease is neoplasm.