Up-regulation of cyclin D2 enhances cell cycle progression in t(14;16) cases [24, 25] and a high proliferative index [13, 26], whereas upregulation of ITGB7 and CCR1 stimulates MM growth via enhancing MM cell adhesion to stromal cells and cytokine secretion [27, 28]. The gene discussed is CCND2; the disease is Miyoshi myopathy.