Our target analysis identified previously reported genes in this pathway, significantly identified following virulent and attenuated infection, such as SHIP-1, VAV3 and VAMP3 suggested to be downregulated by mmumiR-155-5p, and PTEN, downregulated by mmu-miR-222-3p, involved in phagosome formation and recycling of cell membrane, respectively. The gene discussed is VAV3; the disease is infection.