Five biological processes, Molecular Mechanisms of Cancer, Fcγ Receptormediated Phagocytosis in Macrophages, PI3K/AKT Signaling, PTEN Signaling and Role of Macrophages in Rheumatoid Arthritis are potentially regulated by miRNAs in response to L. interrogans infection, regardless of virulence. This evidence concerns the gene PTEN and cancer.