Five biological processes, Molecular Mechanisms of Cancer, Fcγ Receptormediated Phagocytosis in Macrophages, PI3K/AKT Signaling, PTEN Signaling and Role of Macrophages in Rheumatoid Arthritis are potentially regulated by miRNAs in response to L. interrogans infection, regardless of virulence. The gene discussed is AKT1; the disease is cancer.