Immuno-phenotypically, splenic hemangiomas show reactivity of the endothelial lining cells of the vascular markers CD31, Von Willebrand factor, Ulex europaeus lectin I, and CD34.[23] Other types of splenic hemangioma include venous hemangioma, benign (infantile) hemangioendothelioma, and diffuse sinusoidal hemangiomatosis. The gene discussed is PECAM1; the disease is splenic hemangioma.