Moreover, recent researches in the field of genetics suggest that PCV may not be as closely related to AMD, such as its differential risk to a mutation in FGD6, viralicidic activity 2-like (SKIV2L), complement component 3 (C3), elastin (ELN), and apolipoprotein E (APOE) [12–16]. Here, C3 is linked to age-related macular degeneration.