We found that in Asian population, CETP rs3764261 (T allele; OR = 1.46; 95% CI: 1.28–1.665, P < 0.01), CETP rs2303790 (G allele; OR = 1.57; 95% CI: 1.258–1.96, P < 0.01), and ABCG1 rs57137919 (A allele; OR = 1.168; 95% CI: 1.016–1.343, P < 0.01) were significantly associated with PCV, and ABCG1 rs57137919 (A allele; OR = 1.208, 95% CI: 1.035–1.411, P < 0.01) has different effects in PCV and AMD. The gene discussed is ABCG1; the disease is age-related macular degeneration.