Therefore, dysfunction of CETP, LIPC, LPL, ABCA1, and ABCG1 may cause accumulation of oxidized lipids in the retina, and the unreasonable products could induce inflammation and vascular anomaly, which play a crucial role in the development of PCV and AMD via lipid metabolism [53, 54]. Here, ABCG1 is linked to age-related macular degeneration.