Genetic studies in the HDLMP with PCV and AMD have identified susceptibility single nucleotide polymorphisms (SNPs) in multiple genes, including rs3764261/rs2303790 in CETP, rs493258/rs10468017 in LIPC, rs12678919 in LPL, rs1883025 in ABCA1, and rs57137919 in ABCG1. This evidence concerns the gene ABCG1 and age-related macular degeneration.