Established cell line models have similar patterns: the LNCaP cell line does not have an amplification of 8q (Supplementary Table 4); however, the commonly used metastatic PCa cell line PC3 has amplifications in NCOA2, MYC, and YWHAZ, which is suggestive of an 8q amplification. This evidence concerns the gene NCOA2 and posterior cortical atrophy.